Korsch B M
Klin Padiatr. 1983 Jul-Aug;195(4):252-5. doi: 10.1055/s-2008-1034378.
In terms of physical health, degree of rehabilitation and the personal assessment of the affected patients, kidney transplantation represents the optimal therapy for children with chronic renal insufficiency. The best results are achieved by transferring organs from relatives. However, this can only be accomplished if medical treatment is accompanied and supported by continuous psychosocial care of the patient, the family and the treatment team. The problem of noncompliance requires special attention, since it may be the reason for rejection of transplants; it can, however, be recognized by preliminary preventive investigations and prevented by appropriate therapy. Our positive overall experience concerning parenthood following kidney transplants does not appear to justify dissuading such patients from having children if they so wish. However, we consider that especially young women who already have impaired function with a transplanted kidney should be advised of the risk of further deterioration during pregnancy, and that the possibility of reduced life expectancy should be discussed with these patients as a matter of urgency.
就身体健康、康复程度以及受影响患者的个人评估而言,肾移植是慢性肾功能不全儿童的最佳治疗方法。亲属供肾能取得最佳效果。然而,只有在患者、家庭和治疗团队得到持续的心理社会护理陪伴和支持的情况下,这一点才能实现。不依从问题需要特别关注,因为它可能是移植排斥的原因;不过,通过初步的预防性调查可以识别该问题,并通过适当的治疗加以预防。我们在肾移植后生育方面的总体积极经验似乎并不足以劝阻有此意愿的此类患者生育。然而,我们认为,尤其对于移植肾功能已经受损的年轻女性,应告知其怀孕期肾功能进一步恶化的风险,并应尽快与这些患者讨论预期寿命缩短的可能性。