Schroeder T M, Elkins R C, Greenfield L J
Surgery. 1978 Apr;83(4):435-9.
Clinical studies demonstrating the effectiveness of the Kim-Ray Greenfield vena caval filter in the management of pulmonary emboli have stimulated efforts to accurately define this filter's capability to entrap sized emboli and maintain caval patency. Twenty-three dogs had filters inserted and positioned distal to the renal veins. Radiopaque emboli measuring 2 to 5 mm were introduced via the femoral vein. Cineradiography allowed direct observation of emboli capture and filter flow dynamics. Probability of entrapment was found to be related to (1) emboli size, (2) depth of filling of the conical-shaped filter by prior entrapment of emboli, and (3) absence of distal venous hypertension. The geometric design of the filter, which allows progressive vertical filling while maintaining circumferential blood flow, is thought to be responsible for entrapment of emboli and avoidance of venous thrombosis and hypertension.
临床研究表明,金雷·格林菲尔德腔静脉滤器在治疗肺栓塞方面具有有效性,这激发了人们努力准确界定该滤器捕获不同大小栓子以及维持腔静脉通畅的能力。23只狗被植入滤器,并将其放置在肾静脉远端。通过股静脉引入直径为2至5毫米的不透X线栓子。电影血管造影术可直接观察栓子捕获情况及滤器内血流动力学。发现栓子被捕获的概率与以下因素有关:(1)栓子大小;(2)先前捕获的栓子使圆锥形滤器填充的深度;(3)远端静脉无高血压。滤器的几何设计能在保持圆周血流的同时实现逐渐垂直填充,这被认为是栓子得以捕获并避免静脉血栓形成和高血压的原因。