[Neurologic adverse manifestations and complications of ambulatory therapy with psychotropic drugs in the late stages].

Neurological side-effects and complications were studied in 100 patients having undergone long-term (3--14 years) out-patient treatment. In 14 cases there were slight side-effects. In patients of old age, after 6 year lithium treatment there were extrapyramidal signs, disturbances of memory and disorders of orientation in place. In 1 case following 2 year treatment with small doses of neuroleptical drugs there was an oral dyskinesia, after which an overdosage with antidepressive drugs and tranquillizers led to an akineticohypotonic syndrome. The side-effects and complications had a reversible character. Recommendations for therapy of such complications are given.