Salonen J T, Puska P, Kottke T E, Tuomilehto J, Nissinen A
Br Med J (Clin Res Ed). 1983 Jun 11;286(6381):1857-60. doi: 10.1136/bmj.286.6381.1857.
The trends in mortality from coronary heart disease in the 1970s and the differences in trends between counties within Finland were calculated from official mortality statistics among the population aged 35 to 64 years. During this period coronary mortality declined by a mean of 1.1% for men and 2.3% for women annually in the whole of Finland. A community based cardiovascular control programme was started in 1972 in North Karelia, a county in the east of Finland. The decline in coronary mortality in this county between 1969 and 1979 was 24% in men and 51% in women. The decline in the rest of Finland over the same period was 12% in men and 24% in women. The decline in North Karelia was greater than that in other counties of Finland for both men and women and that difference exceeded random variation, with over 95% likelihood for both sexes. Even with adjustment for rates before 1974 with cross-county multiple regression analyses the difference persisted. Although further studies are needed, the changes in coronary mortality in North Karelia suggest that the preventive programme has been effective.
冠心病死亡率在20世纪70年代的趋势以及芬兰各县之间趋势的差异,是根据官方对35至64岁人群的死亡率统计数据计算得出的。在此期间,芬兰全国男性冠心病死亡率平均每年下降1.1%,女性下降2.3%。1972年,在芬兰东部的北卡累利阿地区启动了一项基于社区的心血管疾病控制项目。1969年至1979年期间,该地区男性冠心病死亡率下降了24%,女性下降了51%。同期芬兰其他地区男性下降了12%,女性下降了24%。北卡累利阿地区男性和女性的死亡率下降幅度均大于芬兰其他县,且这种差异超出了随机变化范围,两性的可能性均超过95%。即使通过跨县多元回归分析对1974年之前的发病率进行调整,差异仍然存在。尽管还需要进一步研究,但北卡累利阿地区冠心病死亡率的变化表明预防项目是有效的。