抗 Jo-1 抗体：伴间质性肺病的肌炎的标志物。
Anti-Jo-1 antibody: a marker for myositis with interstitial lung disease.
作者信息
Bernstein R M, Morgan S H, Chapman J, Bunn C C, Mathews M B, Turner-Warwick M, Hughes G R
出版信息
Br Med J (Clin Res Ed). 1984 Jul 21;289(6438):151-2. doi: 10.1136/bmj.289.6438.151.
Abstract
An autoantibody known as anti-Jo-1 antibody is found in 25% of patients with myositis. Its prevalence in patients with both myositis and cryptogenic fibrosing alveolitis was 68% (13 out of 19 patients), compared with 7.5% in patients with myositis alone (four of 53) and 3% in patients with cryptogenic fibrosing alveolitis alone (two of 62). Anti-Jo-1 antibody may be useful in indicating patients with myositis and cryptogenic fibrosing alveolitis. Raynaud's phenomenon, the sicca syndrome, and mild arthritis are also often part of the syndrome.
摘要
一种名为抗Jo-1抗体的自身抗体在25%的肌炎患者中被发现。在患有肌炎和隐源性纤维性肺泡炎的患者中，其患病率为68%（19例患者中有13例），而单独患有肌炎的患者中为7.5%（53例中有4例），单独患有隐源性纤维性肺泡炎的患者中为3%（62例中有2例）。抗Jo-1抗体可能有助于诊断患有肌炎和隐源性纤维性肺泡炎的患者。雷诺现象、干燥综合征和轻度关节炎也常常是该综合征的一部分。
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本文引用的文献
1
Heterogeneity of precipitating antibodies in polymyositis and dermatomyositis. Characterization of the Jo-1 antibody system.
Arthritis Rheum. 1980 Aug;23(8):881-8. doi: 10.1002/art.1780230802.
2
Cryptogenic fibrosing alveolitis: clinical features and their influence on survival.
Thorax. 1980 Mar;35(3):171-80. doi: 10.1136/thx.35.3.171.
3
Identification of antibodies to acidic antigens by counterimmunoelectrophoresis.
Ann Rheum Dis. 1982 Oct;41(5):554-5. doi: 10.1136/ard.41.5.554.
4
A systematic controlled study of pulmonary abnormalities in rheumatoid arthritis.
J Rheumatol. 1983 Jun;10(3):395-405.
5
Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity.
Nature. 1983;304(5922):177-9. doi: 10.1038/304177a0.
6
Osteitis condensans ilii in apatite crystal deposition disease.
Arthritis Rheum. 1983 Apr;26(4):567-9. doi: 10.1002/art.1780260420.
7
Remission from polymyositis after total body irradiation.
Br Med J (Clin Res Ed). 1982 Jun 26;284(6333):1915-6. doi: 10.1136/bmj.284.6333.1915.
8
The precipitating antibody to an acidic nuclear protein antigen, the Jo-1, in connective tissue diseases. A marker for a subset of polymyositis with interstitial pulmonary fibrosis.
Arthritis Rheum. 1983 May;26(5):604-11. doi: 10.1002/art.1780260505.
9
Interstitial lung disease in polymyositis and dermatomyositis: analysis of six cases and review of the literature.
Medicine (Baltimore). 1976 Jan;55(1):89-104. doi: 10.1097/00005792-197601000-00005.
10
Polymyositis and dermatomyositis (first of two parts).
N Engl J Med. 1975 Feb 13;292(7):344-7. doi: 10.1056/NEJM197502132920706.
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