Wesener K, Doppelfeld E, Winkler C
Nuklearmedizin. 1978 Mar;17(1):1-8.
Two mathematical models are employed to describe and interpret the time-activity course in the human body outside the reno-vesical compartment of a tracer that has been injected intravenously by the single-shot method and is excreted via the kidneys. From the results a method is derived which permits a practical determination of total clearance. The individual clearance of each kidney is calculated using a simplified method of background (EPA) correction.
采用两种数学模型来描述和解释通过单次静脉注射进入人体并经肾脏排泄的示踪剂在肾膀胱腔外的时间-活性过程。根据这些结果推导出一种方法,该方法可用于实际测定总清除率。使用一种简化的背景(EPA)校正方法来计算每个肾脏的个体清除率。