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[恶性小脑梗死]

[Malignant cerebellar infarct].

作者信息

Keidel M, Galle G, Wiedmayer J, Taghavy A

出版信息

Fortschr Neurol Psychiatr. 1984 Aug;52(8):277-83. doi: 10.1055/s-2007-1002025.

Abstract

Three patients with cerebellar infarcts and secondary obstructive hydrocephalus (hydrocephalus occlusus) are described, the condition being due to the space-occupying action of the ischaemia and oedema zone with compression and displacement of the fourth ventricle and/or obstruction of the aqueduct. Possible brain stem compression and danger of cerebellar tonsillar herniation were present. From the acute deterioration of the clinical picture, particularly of the state of consciousness, as well as from the findings obtained via computed tomography showing a widening of the inner ventricular space, it was imperative to perform emergency pressure-relieving drainage surgery with ventriculo-atrial shunts in all the cases described. The first two patients could be discharged postoperatively with successful treatment, only slight neurological disturbances remaining. This leads to the conclusion that a (malignant) cerebral infarct should be treated as an emergency case, in a somewhat similar way as in cases of cerebellar haemorrhage or other space-occupying lesions in the posterior fossa of the skull. To recognize the life-threatening exacerbation, sufficient observation and supervision will be necessary. Rapid deterioration in consciousness should be considered a sign of increasing intracranial pressure progressing with the development of hydrocephalus internus occlusus. After neuroradiological diagnosis, especially after verification via computed tomography, this should be interpreted as an indication for immediate neurosurgical intervention. This is the only way to keep the mortality rate satisfactorily low. Dichotomy of cerebellar infarcts into a benign type with spontaneous decrease of symptoms and signs, and a malignant type with development of hydrocephalus internus and increased intracranial pressure, such as in the cases described here, is suggested.

摘要

本文描述了3例小脑梗死继发梗阻性脑积水(脑积水性梗阻)的患者,病因是缺血和水肿区域的占位作用,导致第四脑室受压和移位及/或导水管梗阻。存在脑干受压及小脑扁桃体疝形成的风险。鉴于临床症状尤其是意识状态急剧恶化,以及计算机断层扫描结果显示脑室内部空间增宽,所有病例均必须紧急行脑室-心房分流减压引流手术。前两名患者术后成功治愈出院,仅遗留轻微神经功能障碍。由此得出结论,(恶性)脑梗死应作为急症处理,方式与小脑出血或颅骨后窝其他占位性病变类似。为识别危及生命的病情加重情况,充分的观察和监护必不可少。意识迅速恶化应被视为颅内压升高伴梗阻性内脑积水进展的征象。经神经放射学诊断,尤其是经计算机断层扫描证实后,应将其解读为立即进行神经外科干预的指征。这是将死亡率维持在令人满意的低水平的唯一方法。本文建议将小脑梗死分为良性型(症状和体征自发减轻)和恶性型(如本文所述病例,出现梗阻性内脑积水和颅内压升高)。

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