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[传染性鼻炎临床病例及分离出的嗜血杆菌菌株特性]

[Clinical cases of infectious coryza and the properties of isolated Haemophilus strains].

作者信息

Giurov B

出版信息

Vet Med Nauki. 1984;21(7-8):22-30.

PMID:6506456
Abstract

Studied were a total of sixteen cases with the clinical picture of coryza. Leading role in eleven of them had Haemophilus, in one the signs of chronical cholera and pox were seen, and in three there was a Pseudomonas aeruginosa infection. All cases were serologically positive for CRD. By their needs of nutrient growth factors the isolated Haemophilus strains belonged to H. paragallinarum, and they proved pathogenic for 8-week-old birds and poults that were about to lay their first eggs, killing 4-7-day-old chick embryos up to the 48 h hour. Tests for resistance to therapeutic means with the use of the disk-diffusion method revealed sensitivity to streptomycin, tetracycline, chloramphenicol, gentamycin, erythromycin, spectinomycin, furazolidon, imekil, cosumix, trimetoprim, and sulfadoxin. Good and very good therapeutic and prophylactic effects were produced with the use of sulfotin, cosumix, linkospectin, and trimedin coupled with aerosol disinfection with rivanol, the birds being present on the premise. It is stated that with regard to differential diagnosis coryza caused by Haemophilus paragallinarum should not be confused with fowl cholera, pox, CRD, and Pseudomonas aeruginosa infection which may run their course in a mixed infection.

摘要

共研究了16例具有鼻炎临床症状的病例。其中11例主要由嗜血杆菌引起,1例可见慢性霍乱和痘疹迹象,3例存在铜绿假单胞菌感染。所有病例的慢性呼吸道疾病血清学检测均呈阳性。分离出的嗜血杆菌菌株根据其营养生长因子需求属于副鸡嗜血杆菌,它们对8周龄的鸡和即将产蛋的雏鸡具有致病性,可在48小时内致4至7日龄的鸡胚死亡。采用纸片扩散法进行的治疗手段耐药性测试显示,这些菌株对链霉素、四环素、氯霉素、庆大霉素、红霉素、壮观霉素、呋喃唑酮、伊美克、考苏米克斯、甲氧苄啶和磺胺多辛敏感。使用磺胺托辛、考苏米克斯、林可壮观霉素和曲美汀并结合利凡诺气雾剂消毒(鸡在场的情况下)可产生良好和非常好的治疗及预防效果。文中指出,关于鉴别诊断,由副鸡嗜血杆菌引起的鼻炎不应与禽霍乱、痘疹、慢性呼吸道疾病以及可能在混合感染中发生的铜绿假单胞菌感染相混淆。

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