Mustafina R Kh
Med Radiol (Mosk). 1984 Dec;29(12):33-8.
Using solid tumors RS-1, Pliss' lymphosarcoma and Guerin's carcinoma it has been noted that growth rates of tumors of different size are reverse proportional to their size: the less a tumor is, the faster its growth rate and a more pronounced therapeutic effect of x-ray irradiation are. A radiation dose fractionation regimen produces a considerable effect on the therapeutic efficacy under the conditions of experimental radiation therapy: with adhering to the general therapeutic scheme the initial irradiation of tumor at a dose of 6 Gy two times every other day proved to be more effective than daily irradiation at a dose of 4 Gy for 3 days.
利用实体瘤RS - 1、普利斯氏淋巴肉瘤和格林氏癌,已注意到不同大小肿瘤的生长速率与其大小成反比:肿瘤越小,其生长速率越快,X射线照射的治疗效果越明显。在实验性放射治疗条件下,放射剂量分割方案对治疗效果有显著影响:在遵循总体治疗方案的情况下,每隔一天以6 Gy的剂量对肿瘤进行两次初始照射,比连续3天每天以4 Gy的剂量照射更有效。