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伴有大片坏死及鳞状化生的腺淋巴瘤。

Adenolymphoma with massive necrosis and squamous metaplasia.

作者信息

Weiss L M, Brodsky G L

出版信息

Acta Pathol Jpn. 1984 Nov;34(6):1469-74. doi: 10.1111/j.1440-1827.1984.tb00571.x.

Abstract

A 61-year-old female presented with a longstanding parotid mass with recent change in size. Histologically, the mass was composed of extensively necrotic tissue with a peripheral rim of ribbons of epithelium. In one focus, a double layer of oxyphilic epithelium overlying a lymphoid stroma in a papillary configuration was present, establishing the diagnosis of adenolymphoma (AL). The possibility of infarction and/or infection complicating AL is discussed. In any parotid gland lesion clinically presenting as a longstanding tumor with recent change clinically suggestive of infarction and/or infection, the diagnosis of AL should be considered. In the pathologic specimen with extensive necrosis, areas of preserved epithelium and stroma should be searched for carefully to confirm the diagnosis.

摘要

一名61岁女性因长期存在的腮腺肿块且近期大小发生变化前来就诊。组织学检查显示,肿块由广泛坏死组织构成,周边有上皮条索。在一个病灶中,可见一层嗜酸性上皮覆盖在呈乳头状结构的淋巴样间质上,从而确诊为腺淋巴瘤(AL)。文中讨论了AL并发梗死和/或感染的可能性。对于任何临床上表现为长期存在的肿瘤且近期出现提示梗死和/或感染的临床变化的腮腺病变,都应考虑AL的诊断。在有广泛坏死的病理标本中,应仔细寻找保存的上皮和间质区域以确诊。

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