Gryboś M
Arch Immunol Ther Exp (Warsz). 1984;32(4):397-403.
The present experiments were carried out with the aim to determine G, A and M immunoglobulin concentration levels in the blood serum of parturients, umbilical blood of their neonates, and in the amniotic fluid in 17 women with prolonged pregnancies. The diagnosis of prolonged pregnancy was confirmed by the typical after term traits in infants. IgG and IgA were detected in all three environments and the presence of IgM was confirmed in all cases in the blood serum and in 76% of the tested samples of amniotic fluid. IgG concentration in the blood serum of mothers with prolonged pregnancy was lower than in physiological pregnancies. Despite this IgG level in the serum of umbilical blood of the neonates was normal in all cases. The values of IgA and IgM were noted to be normal both in the parturients' blood serum as well as in the umbilical blood. Examination of the amniotic fluid did not reveal significant differences in immunoglobulin levels related to the duration of full term pregnancy compared to prolonged pregnancy.
本实验旨在测定17例过期妊娠妇女血清、新生儿脐血及羊水中的G、A和M免疫球蛋白浓度水平。过期妊娠的诊断通过婴儿典型的过期特征得以证实。在所有三种环境中均检测到IgG和IgA,并且在所有血清病例以及76%的羊水检测样本中均证实存在IgM。过期妊娠母亲血清中的IgG浓度低于生理性妊娠。尽管如此,所有病例中新生儿脐血血清中的IgG水平均正常。产妇血清和脐血中的IgA和IgM值均正常。与过期妊娠相比,对羊水的检查未发现与足月妊娠持续时间相关的免疫球蛋白水平存在显著差异。