Zárandy B, Szabó J, Molnár I, Sallai Z, Simon Z, Légrády J
Z Urol Nephrol. 1984 Oct;77(10):599-603.
Following surgical removal of papillary tumours of the bladder from 60 patients the authors performed short instillations of the bladder with LYCURIM. The histological picture revealed tumours in the stage O-A-B1 and grade I-II-III. In a control group (n = 129) 89 recidive cases were observed in 2 years. Out of the 60 patients of the LYCURIM group 19 (31.7%) were free of tumours for 2 years and 43 (71.7%) for 11/2 years. A transient cystitis which occurred with short application of the medicament was easily cured. Toxic effects on the blood picture were not observed.
在对60例患者进行膀胱乳头状瘤手术切除后,作者用LYCURIM对膀胱进行了短期灌注。组织学检查显示肿瘤处于O - A - B1期,分级为I - II - III级。在对照组(n = 129)中,2年内观察到89例复发病例。在LYCURIM组的60例患者中,19例(31.7%)2年无肿瘤,43例(71.7%)1.5年无肿瘤。药物短期应用时出现的短暂性膀胱炎很容易治愈。未观察到对血常规的毒性作用。