Blondeel A
Ann Dermatol Venereol. 1983;110(6-7):513-22.
The computer analysis of a sample collecting 2,028 patients suffering from an eczematous dermatitis and subordinated to epicutaneous tests allowed us to analyze the rather difficult question of cosmetic allergy. This allergy is observed only in 2 p. 100 of the cases, if one considers the cosmetic allergy isolated; it reaches 5 p. 100 if it is associated with allergens coming from other origins (drugs of professional). However, in a more selected population of 91 patients suffering from a face dermatitis, these levels reach respectively 25 and 43 p. 100. The respective role of topic drugs and cosmetics is studied as well as main allergens associated with cosmetic allergy. The good tolerance of cosmetics encountered in patients allergic to one of their presumed components seems paradoxical. A prevention model of cosmetic allergy is presented, with an hypoallergenic variety of lanolin.
对2028例患有湿疹性皮炎并接受皮肤试验的患者样本进行计算机分析,使我们能够分析化妆品过敏这一相当棘手的问题。如果仅考虑单纯的化妆品过敏,在这些病例中仅0.02%观察到这种过敏;如果与来自其他来源(职业性药物)的过敏原相关联,其发生率可达0.05%。然而,在91例面部皮炎患者这一经过更严格筛选的人群中,这些水平分别达到25%和43%。还研究了外用药物和化妆品各自的作用以及与化妆品过敏相关的主要过敏原。对假定的某种成分过敏的患者中化妆品的良好耐受性似乎自相矛盾。提出了一种化妆品过敏预防模型,采用低变应原性的羊毛脂品种。