对乙酰氨基酚对吲哚美辛抗炎、解热和镇痛活性的影响。
The influence of paracetamol on the anti-inflammatory, the anti-pyretic and the analgesic activity of indomethacin.
作者信息
van Kolfschoten A A, Hagelen F, Hillen F C, van Noordwijk J
出版信息
Arch Int Pharmacodyn Ther. 1983 Sep;265(1):55-60.
PMID:6651406
Abstract
Interactions between indomethacin (INDO) and paracetamol (PAR) with regard to their anti-inflammatory, anti-pyretic and analgesic activities were studied in rats. The anti-inflammatory and anti-pyretic effects of INDO and PAR were additive. Although antagonism was observed in the analgesic test, the effect of the combination was not inferior to that of PAR alone.
摘要
在大鼠中研究了吲哚美辛（INDO）与对乙酰氨基酚（PAR）在抗炎、解热和镇痛活性方面的相互作用。吲哚美辛和对乙酰氨基酚的抗炎和解热作用是相加的。虽然在镇痛试验中观察到拮抗作用，但联合用药的效果并不低于单独使用对乙酰氨基酚的效果。
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