苯酚溶液能差异性地阻断猫皮肤神经纤维的传导。

Phenol solutions differentially block conduction in cutaneous nerve fibers of the cat.

作者信息

Dodt H U, Strichartz G R, Zimmermann M

出版信息

Neurosci Lett. 1983 Dec 11;42(3):323-7. doi: 10.1016/0304-3940(83)90282-3.

Abstract

The action of phenol in Tyrode solution on nerve conduction has been investigated in vivo in the desheathed sural nerve of cats. A section of 8 mm of the nerve was exposed to phenol solution. At low phenol concentrations (0.05-0.125%) a reversible block of A- and C-fibers occurred. At higher concentrations (0.6-1%) a selective and persistent C-fiber block could be achieved. The size of the residual A-volley was between 50% and 81% when all C-fibers were blocked.

摘要

已在猫的去鞘腓肠神经上对苯酚在台氏液中对神经传导的作用进行了体内研究。将一段8毫米长的神经暴露于苯酚溶液中。在低苯酚浓度（0.05 - 0.125%）时，A纤维和C纤维出现可逆性阻滞。在较高浓度（0.6 - 1%）时，可实现选择性且持久的C纤维阻滞。当所有C纤维被阻滞后，残余A波群的大小在50%至81%之间。