Muralidhara D V, Shetty P S
Indian J Physiol Pharmacol. 1983 Oct-Dec;27(4):345-9.
A simple and reliable closed circuit apparatus for short term and long term measurements of oxygen consumption of small laboratory animals is described. Repeat measurements of oxygen consumption under resting conditions of six male albino rats using this apparatus shows a variability of less than 1.5%. Use of the set-up for continuous monitoring of oxygen consumption following subcutaneous injection of norepinephrine, for over 2.5 hr enables the measurement of energy expenditure in animals on a long term basis which is reproducible on several occasions.
本文描述了一种用于短期和长期测量小型实验动物耗氧量的简单可靠的闭路装置。使用该装置对六只雄性白化大鼠在静息状态下的耗氧量进行重复测量,结果显示其变异性小于1.5%。使用该装置对皮下注射去甲肾上腺素后的动物耗氧量进行超过2.5小时的连续监测,能够长期测量动物的能量消耗,并且在多个实验中具有可重复性。