新西兰白兔在畸形学中的应用：自发和药物诱导畸形的发生率。
Use of the New Zealand white rabbit in teratology: incidence of spontaneous and drug-induced malformations.
作者信息
Stadler J, Kessedjian M J, Perraud J
出版信息
Food Chem Toxicol. 1983 Oct;21(5):631-6. doi: 10.1016/0278-6915(83)90151-5.
PMID:6686190
Abstract
Cumulative data are presented on the occurrence of external, skeletal and visceral abnormalities in foetuses from teratology studies conducted in New Zealand White rabbits over a 10-yr period. The data, based on examinations of over 5500 control foetuses and 19,000 foetuses from treated dams, are derived from studies involving 58 compounds, five of which were judged to be teratogenic.
摘要
呈现了在10年期间对新西兰白兔进行的致畸学研究中胎儿出现的外部、骨骼和内脏异常的累积数据。这些数据基于对5500多个对照胎儿和来自经处理母鼠的19000个胎儿的检查，来自涉及58种化合物的研究，其中5种被判定具有致畸性。
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