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[大鼠出生后个体发育过程中的脊髓局部电位]

[Focal spinal cord potentials in the postnatal ontogeny of the rat].

作者信息

Bursian A V

出版信息

Zh Evol Biokhim Fiziol. 1984 Jan-Feb;20(1):54-60.

PMID:6702353
Abstract

Single stimulation of n. tibialis in rat puppies during the first month of their postnatal life more than 4-fold increases the amplitude of the negative deflection of the cord dorsum potential and almost 2.5 times decreases its duration. Due to a significant increase in the conduction velocity along the fastest afferents, the latent period decreases approximately by 6 times. In newborn rats, gradual pattern of the reaction to the increasing stimulation is manifested rather poorly. Focal potentials recorded during the impalement of microelectrode into the dorsal part of the spinal cord, include a complex of negative deflections of one pre- and three postsynaptic components which differ with respect to their latent periods, maximum localization and relation to the strength of a stimulus. These components are differentiated quite well already to the end of the second week of postnatal life. During the first week, focal potentials exhibit long latent periods of maxima and low amplitude.

摘要

在新生大鼠出生后的第一个月内,对其胫神经进行单次刺激,可使脊髓背侧电位负向偏转的幅度增加4倍以上,其持续时间缩短近2.5倍。由于沿最快传入神经的传导速度显著增加,潜伏期缩短约6倍。在新生大鼠中,对逐渐增强的刺激的反应模式表现得相当不明显。将微电极刺入脊髓背侧时记录到的局部电位,包括一个由一个突触前成分和三个突触后成分组成的负向偏转复合体,它们在潜伏期、最大定位以及与刺激强度的关系方面存在差异。这些成分在出生后第二周结束时就已经很好地分化了。在第一周内,局部电位的最大值潜伏期长且幅度低。

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