缺磷对喂食和禁食大鼠体外葡萄糖诱导的胰岛素释放的影响。
Effect of phosphate omission on the glucose-induced insulin release in vitro in fed and fasted rats.
作者信息
Castillo M, Campillo J E, Martinez Valdivia M, Osorio C
出版信息
Acta Diabetol Lat. 1982 Jul-Sep;19(3):281-3. doi: 10.1007/BF02624688.
PMID:6756007
Abstract
Isolated perfused rat pancreases from fed and 20-h fasted rats were used to investigate the effect of phosphate omission on the insulin response to 16.7 mmol/l glucose. The insulin response to continuous glucose stimulation was biphasic. Both phases were significantly reduced when pancreases were perfused in the absence of extracellular phosphate in fasted, but not in fed rats.
摘要
采用来自喂食大鼠和禁食20小时大鼠的离体灌注胰腺，以研究缺磷对胰岛素对16.7 mmol/L葡萄糖反应的影响。胰岛素对持续葡萄糖刺激的反应呈双相性。在禁食大鼠中，当胰腺在无细胞外磷酸盐的情况下灌注时，两个阶段均显著降低，但在喂食大鼠中则不然。
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