Kaffarnik H, Schneider J, Schubotz R, Zöfel P
MMW Munch Med Wochenschr. 1980 Jan 18;122(3):95-8.
The stabilization parameters of patients under routine care are differentiated. 20 hyperlipoproteinemic patients (types IIa, IIb and IV) who were difficult to stabilize were treated with 0.9 g etofibrate daily. In addition to the cholesterold and triglyceride levels, we followed up the laboratory control parameters in the serum, fasting blood sugar and differential blood count. During the treatment period the cholesterol levels fell to 18%, triglycerides to 50%. Tachyphylaxis was never seen. The good tolerance of etofibrate shows that the substance is suitable as a potent hypolipidemic agent for longterm treatment of hyperlipoproteinemia.
接受常规护理的患者的稳定参数存在差异。20名难以稳定病情的高脂蛋白血症患者(IIa型、IIb型和IV型)每天接受0.9克益多酯治疗。除胆固醇和甘油三酯水平外,我们还跟踪了血清中的实验室对照参数、空腹血糖和血细胞分类计数。在治疗期间,胆固醇水平下降了18%,甘油三酯下降了50%。从未出现快速耐受性。益多酯的良好耐受性表明该物质适合作为一种有效的降血脂药物用于高脂蛋白血症的长期治疗。