Influence of various agents on adsorption capacity of kaolin for Pseudomonas aeruginosa toxin.

The in vitro adsorption of 125I-labeled Pseudomonas aeruginosa toxin (I) onto kaolin (II) at various pH values and in the presence of various agents was studied. The maximal adsorption capacity of I onto II occurred at pH values below 4.1, while minimal values were observed at pH 4.1, 7.4, and 8; average adsorption occurred at pH 5 and 6. The tested agents at specific ratios to II decreased the percent adsorption capacity of II for I to various degrees. The results are explained by reference to the structures of both kaolin and the toxin.