Dick W, Ahnefeld F W, Lotz P, Milewski P, Schindewolf H, Wyrwoll K
Anaesthesist. 1980 Aug;29(8):407-13.
PEEP ventilation is frequently used in intensive care patients: its particular effects in the immediate treatment of emergency patients are discussed. In animal experiments different studies were performed using manually operated resuscitators combined with a newly designed PEEP valve. The most important results in neonatal pigs show that the post partum compliances and the neonatal PO2 values were much better after primary PEEP ventilation than after IPPB or 2-phases unfolding inflation. The worst method of respiratory resuscitation is the use of PNPB. In 2 other groups of animals immediate PEEP ventilation was compared to IPPB, after 25 ml of fresh water/kg BW had been instilled into the animals lungs. The PaO2 and AaDO2 values of those animals, treated immediately with PEEP were much better than the corresponding values of the ZEEP group animals. But, the PEEP-treated animals showed a significant reduction of the cardiac output. The article deals further with the results of different authors, as far as PEEP and lung edema, PEEP and CPR, PEEP and shock are concerned. In our opinion, the present clinical and experimental results lead to the following conclusions: The immediate PEEP ventilation at the scene is indicated 1. in neonatal resuscitation - 2. in near drowning - 3. in lung edema - 4. in cardiopulmonary resuscitation. PEEP ventilation should however not exceed 10 cm H2O.
呼气末正压通气(PEEP)常用于重症监护患者:本文讨论了其在急诊患者即刻治疗中的特殊作用。在动物实验中,使用手动操作的复苏器结合新设计的PEEP阀进行了不同的研究。新生猪的最重要结果表明,与间歇正压通气(IPPB)或两阶段展开式充气相比,初次PEEP通气后的产后顺应性和新生儿动脉血氧分压(PO2)值要好得多。最糟糕的呼吸复苏方法是使用部分鼻正压通气(PNPB)。在另外两组动物中,在向动物肺内注入25毫升/千克体重的淡水后,将即刻PEEP通气与IPPB进行了比较。即刻接受PEEP治疗的动物的动脉血氧分压(PaO2)和肺泡-动脉血氧分压差(AaDO2)值比持续气道正压通气(ZEEP)组动物的相应值要好得多。但是,接受PEEP治疗的动物的心输出量显著降低。本文进一步探讨了不同作者关于PEEP与肺水肿、PEEP与心肺复苏、PEEP与休克的研究结果。我们认为,目前临床和实验结果得出以下结论:现场即刻PEEP通气适用于1. 新生儿复苏 - 2. 近乎溺水 - 3. 肺水肿 - 4. 心肺复苏。然而,PEEP通气不应超过10厘米水柱。