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老年心肌梗死后室间隔缺损的修复。早期及长期结果。

Repair of postinfarction ventricular septal defect in the elderly. Early and long-term results.

作者信息

Weintraub R M, Thurer R L, Wei J, Aroesty J M

出版信息

J Thorac Cardiovasc Surg. 1983 Feb;85(2):191-6.

PMID:6823138
Abstract

We performed 13 operations on 12 elderly patients with ventricular septal defect (VSD) following myocardial infarction. All patients were older than 65 years (range 66 to 82 years) and six were over 70 years of age. Ten underwent operation, with counterpulsation support, within 3 weeks of development of the VSD. Among eight patients with anteriorly located VSDs, there were four survivors. Among four patients with inferior defects, three survived. Overall hospital survival was 58%. Hospital costs were no greater in the elderly than in younger patients. The seven long-term survivors were followed up for from 10 months to 7.5 years (mean 3.9 years). There was one sudden death at 7.5 years in a previously well man. Of the remaining six patients, five are in New York Heart Association Class I, and one is in Class II. One woman, now 84 years old, lives independently over 2 years after repair. Our experience with respect to management suggests that unless medical therapy results in continued improvement rather than stability alone, hemodynamic deterioration is inevitable, and survival for delayed repair is unlikely. Furthermore, undue delay frequently results in renal failure and severely compromises the chances for survival after repair in the acute state.

摘要

我们对12例心肌梗死后室间隔缺损(VSD)的老年患者进行了13次手术。所有患者年龄均超过65岁(66至82岁),其中6例年龄超过70岁。10例在VSD出现后3周内接受了手术,并给予反搏支持。在8例室间隔前部缺损的患者中,有4例存活。在4例下壁缺损的患者中,3例存活。总体住院生存率为58%。老年患者的住院费用并不比年轻患者高。7例长期存活者接受了10个月至7.5年(平均3.9年)的随访。一名既往健康的男性在7.5岁时突然死亡。其余6例患者中,5例纽约心脏协会心功能分级为I级,1例为II级。一名现年84岁的女性在修复术后2年多来一直独立生活。我们的治疗经验表明,除非药物治疗能带来持续改善而非仅仅维持稳定,否则血流动力学恶化不可避免,延迟修复的存活可能性不大。此外,过度延迟常常导致肾衰竭,并严重影响急性期修复术后的存活机会。

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