从一名波多黎各妇女严重的慢性皮肤溃疡中分离出扭脱弧菌。

Culture of Vibrio extorquens from severe, chronic skin ulcers in a Puerto Rican woman.

作者信息

Lambert W C, Pathan A K, Imaeda T, Kaminski Z C, Reichman L B

出版信息

J Am Acad Dermatol. 1983 Aug;9(2):262-8. doi: 10.1016/s0190-9622(83)80359-4.

Abstract

A 48-year-old Puerto Rican woman developed extensive ulcers on her buttocks, right arm, and thighs over a 3 1/2-year period. The lesions began as small, subcutaneous nodules which subsequently ulcerated and expanded up to 19 cm in diameter. Biopsy of both ulcerated and nonulcerated lesions showed acid-fast bacilli. Culture of both types of lesions grew Vibrio extorquens, a partially acid-fast methanolophilic organism not previously associated with disease in humans. The patient developed agglutinating antibody, titer 1:80, to this organism. The disease responded to treatment with antibiotics to which the organism was sensitive in vitro.

摘要

一名48岁的波多黎各妇女在3年半的时间里，臀部、右臂和大腿出现了大面积溃疡。病变最初为小的皮下结节，随后溃疡并扩大至直径达19厘米。对溃疡和未溃疡病变进行活检均显示抗酸杆菌。两种病变的培养物均培养出扭脱弧菌，这是一种部分抗酸的嗜甲醇生物，以前未发现与人类疾病有关。患者针对这种生物产生了凝集抗体，效价为1:80。该疾病对抗生素治疗有反应，该生物在体外对这些抗生素敏感。