Lusson J R, Gaulme J, Raynaud E J, Cheynel J
Arch Fr Pediatr. 1982 Aug-Sep;39(7):433-6.
In 11 neonates of diabetic mothers echocardiography was systematically performed and led to the discovery of 6 cases with hypertrophic cardiomyopathy. This abnormality, which may induce cardiorespiratory failure, is usually benign and consists of systolic murmur and transitory cardiomegaly; all these symptoms spontaneously regress within a few weeks. This cardiomyopathy may present with obstructive signs requiring treatment with beta adrenergic blocking agents; however, it is more often pure and needs no treatment. It may be observed after pregnancies that were not well supervised and might be induced by fetal hyperinsulinism.
对11例糖尿病母亲的新生儿进行了系统的超声心动图检查,发现6例肥厚型心肌病。这种异常可能诱发心肺衰竭,通常为良性,表现为收缩期杂音和暂时性心脏扩大;所有这些症状在几周内会自行消退。这种心肌病可能出现梗阻性体征,需要用β肾上腺素能阻滞剂治疗;然而,更多情况下是单纯性的,无需治疗。在孕期监护不佳的情况下可能会观察到这种情况,可能由胎儿高胰岛素血症诱发。