急性淋巴细胞白血病患儿淋巴细胞中阿米巴样运动形态的预后意义
Prognostic significance of amoeboid movement configuration in lymphoid cells from children with acute lymphoblastic leukaemia.
作者信息
Sjögren U, Garwicz S
出版信息
Scand J Haematol. 1980 Apr;24(4):335-9. doi: 10.1111/j.1600-0609.1980.tb01592.x.
Bone marrow smears from 72 consecutive children with a recent diagnosis of acute lymphoblastic leukaemia (ALL) have been morphologically analyzed. A high incidence of lymphoid cells with amoeboid movement configuration (AMC) seems to indicate a more favorable prognosis independently of other prognostic factors e.g. age, WBC or sex. A positive correlation between the AMC and the mitotic indices (MI) of the lymphoblasts indicates some connection between the motility and the proliferative activity of the leukaemic cell clone.
对72名近期诊断为急性淋巴细胞白血病（ALL）的连续儿童的骨髓涂片进行了形态学分析。具有阿米巴样运动形态（AMC）的淋巴细胞高发生率似乎表明，独立于其他预后因素（如年龄、白细胞或性别），预后更有利。AMC与原始淋巴细胞的有丝分裂指数（MI）之间的正相关表明白血病细胞克隆的运动性与增殖活性之间存在某种联系。
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