Lyon J L, Gardner J W, West D W
J Natl Cancer Inst. 1980 Nov;65(5):1063-71.
We compared cancer incidence during 1967--75 between Mormons and non-Mormons living in urban and rural areas of Utah. The non-Mormon urban men had a 34% higher risk of cancer compared with their rural counterparts. Most of this increase in risk occurred in sites associated with tobacco and for cancers of the stomach, colon, and prostate gland. Urban Mormon males had no significant increase in risk. The urban female population was at higher risk than was the rural regardless of religion. The increase was not as striking as that observed in non-Mormon men (8 vs. 34%); cancers of the respiratory and gastrointestinal tracts and female genitalia contributed to the elevated risk. We concluded that personal habits such as smoking and drinking and reproductive factors were possible explanations for the previously observed urban-rural gradients in cancer risk.
我们比较了1967年至1975年间居住在犹他州城乡地区的摩门教徒和非摩门教徒的癌症发病率。与农村的非摩门教男性相比，城市的非摩门教男性患癌风险高34%。这种风险增加大多发生在与烟草相关的部位以及胃癌、结肠癌和前列腺癌。城市摩门教男性的风险没有显著增加。无论宗教信仰如何，城市女性人口的风险都高于农村女性。这种增加不如在非摩门教男性中观察到的那样显著（8%对34%）；呼吸道、胃肠道和女性生殖器官的癌症导致了风险升高。我们得出结论，吸烟、饮酒等个人习惯以及生殖因素可能是此前观察到的癌症风险城乡梯度差异的原因。
