Dodge J A, Hamdi I A, Burns G M, Yamashiro Y
Arch Dis Child. 1981 Sep;56(9):705-7. doi: 10.1136/adc.56.9.705.
Chronic, non-specific `toddler diarrhoea' in young children is often accompanied by an increase in plasma prostaglandins, particularly PGFα. Although treatment with drugs is generally unnecessary, aspirin is effective in most children with high prostaglandins, and treatment with loperamide is effective in most children with toddler diarrhoea, regardless of the plasma prostaglandin levels. The source of the increased plasma prostaglandins is not known.
幼儿慢性非特异性“蹒跚腹泻”常伴有血浆前列腺素升高,尤其是前列腺素Fα。虽然通常无需药物治疗,但阿司匹林对大多数前列腺素水平高的儿童有效,而洛哌丁胺对大多数蹒跚腹泻儿童有效,无论其血浆前列腺素水平如何。血浆前列腺素升高的来源尚不清楚。