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肥胖带绦虫囊尾蚴在几种不同品系大鼠中的生长及抗原性

The growth and antigenicity of the metacestodes of Taenia crassiceps in several different strains of rats.

作者信息

Chernin J

出版信息

J Helminthol. 1981 Sep;55(3):209-22.

PMID:6974186
Abstract

The metacestodes of Taenia crassiceps removed from a stock infection of Sprague Dawley rats were injected into seven inbred and one outbred strain of rats. The results showed that over-all female rats are more susceptible to the infection than male rats. Only one strain of rat, the Lewis male rats, was found to be resistant to the infection. There was no significant differences in the volume of metacestodes recovered from the male and female rats. The sizes of the metacestodes, after two passages through the rats, were compared to those of the original mouse strain and it was found that metacestodes from two strains of rats were significantly smaller. The antigenic expression of the metacestodes from the different strains of rats was compared and some variation in the antigenicity was observed.

摘要

从感染有肥胖带绦虫原头蚴的斯普拉格-道利大鼠中取出原头蚴,将其接种到7个近交系和1个远交系大鼠中。结果表明,总体而言,雌性大鼠比雄性大鼠更易感染。仅发现一种大鼠品系,即刘易斯雄性大鼠对感染具有抗性。从雄性和雌性大鼠中回收的原头蚴体积没有显著差异。将原头蚴在大鼠体内传代两次后的大小与原始小鼠品系的原头蚴大小进行比较,发现来自两种大鼠品系的原头蚴明显更小。对来自不同大鼠品系的原头蚴的抗原表达进行了比较,观察到抗原性存在一些差异。

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