纤溶酶原的基因多态性：一种新的基本变异型（PLG B）及日本人的群体研究
Genetic polymorphism of plasminogen: a new basic variant (PLG B) and population study in Japanese.
作者信息
Nishimukai H, Kera Y, Sakata K, Yamasawa K
出版信息
Vox Sang. 1981;40(6):422-5. doi: 10.1111/j.1423-0410.1981.tb00731.x.
Abstract
Genetic polymorphism of human plasminogen in the Japanese population was studied using agarose gel isoelectric focusing followed by immunofixation. A new basic variant, PLG B, was found as a heterozygous state PLG 1-B, which was genetically determined. The allele frequencies calculated from 258 individuals were PLG1=0.958, PLG2=0.020 and PLGB=0.022.
摘要
利用琼脂糖凝胶等电聚焦结合免疫固定法研究了日本人群中人纤溶酶原的遗传多态性。发现了一种新的碱性变体PLG B，呈杂合状态PLG 1-B，这是由基因决定的。根据258名个体计算出的等位基因频率为PLG1 = 0.958、PLG2 = 0.020和PLGB = 0.022。
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