Hodges I G, Milner A D, Stokes G M
Arch Dis Child. 1981 Oct;56(10):787-9. doi: 10.1136/adc.56.10.787.
A new device, known as the aero-chamber, for delivering aerosol drugs was compared with a standard aerosol inhaler in asthmatic children aged between 5 years 3 months and 13 years 10 months. The study was conducted under double-blind conditions using fenoterol, a beta 2 stimulant, as the active agent and a placebo. Response to treatment was assessed by measuring the peak expiratory flow rate before and after each inhaler. Seven of 10 children had greater mean improvements in peak expiratory flow rates when receiving the active drug from the aerochamber. The aerochamber offers a method for administering a whole range of canistered packaged drugs to children unable to use the standard inhalers.
一种名为雾化吸入器的新型给药装置,用于向年龄在5岁3个月至13岁10个月之间的哮喘儿童输送气雾剂药物,并与标准气雾剂吸入器进行了比较。该研究在双盲条件下进行,使用β2激动剂非诺特罗作为活性剂和安慰剂。通过测量每次吸入前后的呼气峰值流速来评估治疗反应。10名儿童中有7名在使用雾化吸入器吸入活性药物时,呼气峰值流速平均改善更大。雾化吸入器为无法使用标准吸入器的儿童提供了一种给药方法,可用于多种罐装包装药物。