Green S, Field J K, Green C D, Beynon R J
Nucleic Acids Res. 1982 Feb 25;10(4):1411-20. doi: 10.1093/nar/10.4.1411.
The study of nucleic acid hybridization is facilitated by computer mediated fitting of theoretical models to experimental data. This paper describes a non-linear curve fitting program, using the 'Patternsearch' algorithm, written in BASIC for the Apple II microcomputer. The advantages and disadvantages of using a microcomputer for local data processing are discussed.
计算机介导的理论模型与实验数据拟合有助于核酸杂交的研究。本文描述了一个用BASIC语言为苹果II型微型计算机编写的、使用“模式搜索”算法的非线性曲线拟合程序。讨论了使用微型计算机进行局部数据处理的优缺点。