Willemse A, van den Brom W E
Res Vet Sci. 1982 Jan;32(1):57-61.
In 45 normal dogs, serial dilutions of different allergens were injected intradermally to determine the skin threshold concentrations. For housedust, housedust mite (Dermatophagoides pteronyssinus) and human dandruff extracts these were found to be the same in the dog as in man, while those for animal dandruffs, pollens and fungi were 10 times higher in the dog. The term 'histamine reactive value' (RH) is introduced for the dog. The mean (+/-SD) was found to be 49.0 +/- 2.5 in normal dogs, using histamine diphosphate solutions of 0.01, 0.1 and 1 per cent.
在45只正常犬中,将不同变应原进行系列稀释后皮内注射,以测定皮肤阈浓度。对于屋尘、屋尘螨(粉尘螨)和人头皮屑提取物,发现犬与人的皮肤阈浓度相同,而动物头皮屑、花粉和真菌提取物的皮肤阈浓度在犬中比人高10倍。为犬引入了“组胺反应值”(RH)这一术语。使用0.01%、0.1%和1%的磷酸组胺溶液,正常犬的平均(±标准差)组胺反应值为49.0±2.5。