R 因子介导的甲氧苄啶耐药性：两项为期三个月的临床调查结果
R-factor mediated trimethoprim resistance: result of two three-month clinical surveys.
作者信息
Amyes S G, Emmerson A M, Smith J T
出版信息
J Clin Pathol. 1978 Sep;31(9):850-4. doi: 10.1136/jcp.31.9.850.
Abstract
All urinary tract isolates were monitored in the Whittington Hospital, London for trimethoprim resistance over a three-month period in 1975; this survey was repeated 18 months later in 1977. In the later survey the incidence of trimethoprim resistance had increased significantly, and the proportion of strains carrying R-factors conferring trimethoprim resistance had nearly doubled. The pattern of resistances associated with R-factor trimethoprim resistance also changed betweeen these two surveys.
摘要
1975年，伦敦惠廷顿医院对所有泌尿系统分离株进行了为期三个月的甲氧苄啶耐药性监测；1977年，18个月后重复了这项调查。在后来的调查中，甲氧苄啶耐药性的发生率显著增加，携带赋予甲氧苄啶耐药性的R因子的菌株比例几乎翻了一番。在这两次调查之间，与R因子介导的甲氧苄啶耐药性相关的耐药模式也发生了变化。
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