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[温度和pH诱导的相变下磷脂酸双层脂质膜的电导率]

[Conductivity of bilayer lipid membranes of phosphatidic acid at phase transitions, induced by temperature and pH].

作者信息

Antonov V F, Vasserman A N, Mol'nar A A, Kozhomkulov E T, Linke L

出版信息

Biofizika. 1982 Sep-Oct;27(5):822-6.

PMID:7138932
Abstract

Conductivity of bilayer lipid membranes formed from synthetic phosphatic acid and its thioanalogs was studied. Conductivity of bilayer lipid membranes was shown to change spasmodically in the phase transition region. The temperature of conductivity jump decreased with pH shift from acid to alkaline region. The amplitude of conductivity jump attained 1.5-2 orders. The jump can be also obtained at constant temperature by changing the medium pH. The observed conductivity jumps are suggested to determine the phenomena of thermo- and chemoreception in biological membranes.

摘要

对由合成磷酸及其硫代类似物形成的双层脂质膜的电导率进行了研究。结果表明,双层脂质膜的电导率在相变区域会发生痉挛性变化。随着pH值从酸性区域向碱性区域的转变,电导率跳跃的温度降低。电导率跳跃的幅度达到1.5 - 2个数量级。通过改变介质的pH值,也可以在恒定温度下获得这种跳跃。所观察到的电导率跳跃被认为决定了生物膜中的热感受和化学感受现象。

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