Thuriaux M C, Gbetholancy B
Med Trop (Mars). 1982 Sep-Oct;42(5):545-9.
An investigation of lower limb motor disorders among school age children in three rural areas of Niger has demonstrated a prevalence rate of approximately seven per thousand in the 5-9 and 10-14 years age-groups, with no significant difference in rates for boys and girls. Although severe (bilateral) paralysis is encountered only among non-attenders, no significant difference in overall prevalence is found with regard to school attendance status. Eight per cent of affected children are unable to walk and a further eight per cent need crutches or other aids. Patient histories indicate that over 90 per cent of cases occur before the child's fourth birthday; there is no indication of a modification in incidence over the past nine years. Extrapolation from the observed data indicates an annual incidence rate for paralytic poliomyelitis of the order of 45 per hundred thousand population, i.e. about 2,500 cases a year for the whole of Niger, approximately 2,000 of whom survive with a permanent disability. These rates and figures are similar to those calculated for several other african countries and are seven to ten times higher than the figures gathered from routine reports of poliomyelitis in Niger. The total number of children unable to walk unaided among the 5-14 years age-group can be estimated in 1981 at 1,600, half of whom are paralysed in such a way that they are unable to walk at all. Other preventable causes of paralysis of the lower limbs encountered include i.a. tuberculosis of the spine, sequelae of cerebrospinal meningitis and, second only to paralytic poliomyelitis in importance, trauma to peripheral nerves through faulty injection technique.
对尼日尔三个农村地区学龄儿童下肢运动障碍的一项调查表明,5至9岁和10至14岁年龄组的患病率约为千分之七,男孩和女孩的患病率没有显著差异。虽然严重(双侧)瘫痪仅在未上学儿童中出现,但就上学情况而言,总体患病率没有显著差异。8%的患病儿童无法行走,另有8%的儿童需要拐杖或其他辅助器具。患者病史表明,90%以上的病例发生在儿童4岁生日之前;过去九年中发病率没有变化迹象。根据观察数据推断,麻痹性脊髓灰质炎的年发病率约为每十万人口45例,即整个尼日尔每年约2500例,其中约2000例存活但有永久性残疾。这些发病率和数字与其他几个非洲国家计算的结果相似,比尼日尔脊髓灰质炎常规报告收集的数据高7至10倍。据估计,1981年5至14岁年龄组中无法独立行走的儿童总数为1600人,其中一半人瘫痪到根本无法行走的程度。遇到的其他可预防的下肢瘫痪原因包括脊柱结核、脑脊髓膜炎后遗症,以及仅次于麻痹性脊髓灰质炎的因注射技术不当导致的周围神经损伤。