Stewart R M, Samson D, Diehl J, Hinton R, Ditmore Q M
Neurology. 1980 Jan;30(1):47-51. doi: 10.1212/wnl.30.1.47.
Recurrent transient neurologic deficits were evaluated clinically in four patients. In three patients, the symptoms included recurrent transient homonymous hemianopia, episodic weakness and numbness of the left arm and leg, and recurrent sudden loss of speech and of strength in the right arm. In these three patients, the episodes were first thought to be transient ischemic attacks (TIAs). A fourth patient had repeated confusional spells, in which a recurrent musical theme excluded other thoughts. This was associated with dizziness and difficulty in naming. A partial complex seizure was thought responsible. In each of the cases the symptoms lasted less than 30 minutes and were not associated with loss of consciousness, headache, or stiff neck. Electroencephalogram (EEG), brain scan, lumbar puncture, and computed tomography (CT) scan were normal. In all patients, cerebral arteriography unexpectedly revealed an unruptured cerebral aneurysm. The locations of the aneurysms were appropriate to the symptoms, which remitted in the three patients treated surgically for the aneurysm. Although the pathophysiology is uncertain, an ischemic process may be implicated.
对4例患者的复发性短暂性神经功能缺损进行了临床评估。3例患者的症状包括复发性短暂性同向性偏盲、左臂和左腿发作性无力和麻木,以及复发性突然言语丧失和右臂无力。在这3例患者中,发作最初被认为是短暂性脑缺血发作(TIA)。第4例患者反复出现意识模糊发作,其中反复出现的音乐主题排除了其他想法。这与头晕和命名困难有关。认为是部分性复杂性癫痫发作所致。在每例病例中,症状持续时间均不到30分钟,且与意识丧失、头痛或颈部僵硬无关。脑电图(EEG)、脑部扫描、腰椎穿刺和计算机断层扫描(CT)均正常。所有患者的脑血管造影意外发现未破裂的脑动脉瘤。动脉瘤的位置与症状相符,3例接受动脉瘤手术治疗的患者症状缓解。虽然病理生理学尚不确定,但可能涉及缺血过程。