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Mutagenicity studies on fenticonazole, a new antifungal imidazole derivative.

作者信息

Veronese M, Barzaghi D, Bertoncini A, Zadro M

出版信息

Arzneimittelforschung. 1981;31(12):2142-4.

PMID:7199315
Abstract

The forward mutational assay on Schizosaccharomyces pombe and the mitotic gene conversion assay on Saccharomyces cerevisiae were performed in order to verify whether alpha-(2,4-dichlorophenyl)-beta,N-imidazolylethyl 4-phenylthiobenzyl ether nitrate (fenticonazole, Rec 15/1476) shows a potential mutagenicity. In both tests the drug does not seem to possess any mutagenic activity when compared with mutagenic standards.

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