Künzel W
Z Geburtshilfe Perinatol. 1982 Apr-May;186(2):59-64.
From the historical point of view, cord clamping has been performed in natural child birth some time after the fetus has been delivered and after the expulsion of the placenta. In 1877 already Hayem could show that in late cord clamping (LC) the concentration of erythrocytes in the newborn blood is elevated if compared to early clamping (EC) of the unbilical cord. It was concluded that is was a result of placental transfusion. The underlying mechanism of the placental transfusion is the hydrostatic pressure between the placenta and the fetus, supported by uterine contraction and the time of cord clamping after birth. Placental transfusion is diminished if cord clamping is performed in less than 180 sec and if the newborn baby is positioned 20 cm and more above the placental insertion. The newborn responds to placental transfusion with an increase of hemoglobin and hematocrit, an elevated blood pressure, although significant differences in cardiac output could not be established. Renal function is increased and effective renal blood flow associated with the blood volume of the newborn. In cases of caesarean section a higher incidence of respiratory distress occurs if placental transfusion does not take place. In utero placental transfusion occurs if the fetus is hypoxic obviously to increase the oxygen supply to the fetal tissue.
"In order to give the newborn the blood, that it need physiologically cord clamping should be performed not immediately after birth, but one should wait as long until the umbilical vein has been empty and is collapsed." (Bumm 1902).
从历史角度来看,在自然分娩中,脐带结扎是在胎儿娩出且胎盘排出后的一段时间进行的。早在1877年,海姆就已表明,与早期脐带结扎(EC)相比,晚期脐带结扎(LC)时新生儿血液中的红细胞浓度会升高。得出的结论是,这是胎盘输血的结果。胎盘输血的潜在机制是胎盘与胎儿之间的静水压力,辅以子宫收缩以及出生后脐带结扎的时间。如果在180秒内进行脐带结扎,且新生儿位于胎盘附着处上方20厘米及以上,胎盘输血就会减少。新生儿对胎盘输血的反应是血红蛋白和血细胞比容增加、血压升高,尽管心输出量方面未发现显著差异。肾功能增强,有效肾血流量与新生儿血容量相关。在剖宫产的情况下,如果不进行胎盘输血,呼吸窘迫的发生率会更高。如果胎儿明显缺氧,子宫内会发生胎盘输血,以增加对胎儿组织的氧气供应。
“为了给新生儿提供其生理所需的血液,脐带结扎不应在出生后立即进行,而应等待,直到脐静脉排空并塌陷。”(布姆,1902年)