关于饥饿状态下组织对甲状腺激素敏感性的一般评论。
General comments on tissue sensitivity to thyroid hormones in starvation.
作者信息
Burger A G
出版信息
Int J Obes. 1981;5 suppl 1:69-71.
The interrelationship between thyroid hormones and catecholamines is discussed. It is known that hypothyroidism will decrease tissue sensitivity to exogenous catecholamines. There is, however, no experimental proof that the thyroid hormones changes, particularly the low serum T(3) levels encountered in systemic illness and starvation, are sufficient to change tissue sensitivity to catecholamines. Catecholamines and thyroid hormones influence thermogenesis. Recently a decreased effectiveness of thyroid hormones in the starving hypothyroid rat has been documented. It has, however, not been excluded that part of this change is due to a combined change in effectiveness of thyroid hormones and catecholamines on thermogenesis.
本文讨论了甲状腺激素与儿茶酚胺之间的相互关系。已知甲状腺功能减退会降低组织对外源性儿茶酚胺的敏感性。然而，尚无实验证据表明甲状腺激素的变化，尤其是在全身性疾病和饥饿状态下出现的低血清T(3)水平，足以改变组织对儿茶酚胺的敏感性。儿茶酚胺和甲状腺激素会影响产热。最近有文献记载，饥饿的甲状腺功能减退大鼠体内甲状腺激素的效能降低。然而，尚未排除这种变化部分是由于甲状腺激素和儿茶酚胺对产热的联合效能变化所致。
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