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潜伏性弓形虫感染对白色实验大鼠和小鼠学习能力的影响(作者译)

[Effects of a latent Toxoplasma infection on the learning ability in white laboratory rats and mice (author's transl)].

作者信息

Piekarski G, Zippelius H M, Witting P A

出版信息

Z Parasitenkd. 1978 Sep 4;57(1):1-15. doi: 10.1007/BF00927625.

Abstract
  1. Both white laboratory rats and white laboratory mice had a diminished learning capacity in connection with a latent Toxoplasma infection. 2. Five infected couples of rats out of 12 pairs were not able to learn their task by the double-training program in a given period of time. A second group of five rats was able to learn this program but later than the noninfected control-group of brothers and sisters did. 3. Mice seem to be more damaged by Toxoplasma infections than rats in their learning capacity. All infected mice did not reach the same ability than their control brothers and sisters. The reason for this differences could reflect the higher infection rate of the brain of mice than rats during the latent phase of infection.
摘要
  1. 白色实验大鼠和白色实验小鼠在潜伏性弓形虫感染的情况下,学习能力都会下降。2. 12对大鼠中有5对受感染的大鼠无法通过双训练程序在规定时间内学会任务。第二组5只大鼠能够学会这个程序,但比未受感染的同窝对照组大鼠要晚。3. 在学习能力方面,小鼠似乎比大鼠更容易受到弓形虫感染的损害。所有受感染的小鼠都没有达到与其同窝对照小鼠相同的能力。这种差异的原因可能反映出在感染潜伏期,小鼠大脑的感染率高于大鼠。

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