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迪乔治综合征病例中的胸腺植入(作者译)

[Thymus implant in a case of DiGeorge syndrome (author's transl)].

作者信息

Cruz García Rodríguez M, Gracia Bouthelier R, Fontán Casariego G, Lorente Toledano F, Díez Pardo J A, Ojeda Casas J A, Peralta Serrano A

出版信息

An Esp Pediatr. 1978 Nov;11(11):771-6.

PMID:727610
Abstract

A boy with III-IV pharingeal pouch malformative syndrome, hypocalcemia and recurrent infections is presented. The immunological work-up disclosed deficiency in the specific cellular immunity with normal serum immunoglobulin levels. An adult thymus in Millipore diffusion chambers was implanted in the rectus adominalis muscle. One week later clinical and analytical data suggesting immunological reconstitution was recorded. Two years later the patient remains in good health, T and B lymphocyte percentages are normal, being the only immunological abnormality a low serum level of IgG.

摘要

报告了一名患有III-IV咽囊畸形综合征、低钙血症和反复感染的男孩。免疫检查发现特异性细胞免疫缺陷,血清免疫球蛋白水平正常。将置于微孔扩散室中的成人胸腺植入腹直肌。一周后记录到提示免疫重建的临床和分析数据。两年后,患者健康状况良好,T和B淋巴细胞百分比正常,唯一的免疫异常是血清IgG水平较低。

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