Bossingham D H, McQueen A K, Mowat A G
Rheumatol Rehabil. 1981 May;20(2):98-101. doi: 10.1093/rheumatology/20.2.98.
The effect of intra-articular hydrocortisone on knees affected by rheumatoid synovitis has been assessed objectively by the use of an electrogoniometer. The range of flexion during walking has been shown to improve, in some cases into the normal range, and this effect was maintained to a significant degree for eight weeks in a group of 12 patients. Function was shown to improve more slowly than pain and this may have an important bearing on future assessment of anti-inflammatory drugs.ion during walking has been shown to improve, in some cases into the normal range, and this effect was maintained to a significant degree for eight weeks in a group of 12 patients. Function was shown to improve more slowly than pain and this may have an important bearing on future assessment of anti-inflammatory drugs.ion during walking has been shown to improve, in some cases into the normal range, and this effect was maintained to a significant degree for eight weeks in a group of 12 patients. Function was shown to improve more slowly than pain and this may have an important bearing on future assessment of anti-inflammatory drugs. The benefits of hydrocortisone have been measured against intra-articular saline in a single-blind study and shown to be significant both symptomatically and functionally.
已通过使用电子测角仪客观评估了关节内注射氢化可的松对类风湿性滑膜炎累及膝关节的影响。结果显示,步行时的屈曲范围有所改善,在某些情况下已恢复至正常范围,并且在一组12名患者中,这种效果在长达八周的时间里都保持在显著水平。研究表明,功能改善比疼痛缓解更为缓慢,这可能对未来抗炎药物的评估具有重要意义。在一项单盲研究中,已将氢化可的松的疗效与关节内注射生理盐水的疗效进行了对比,结果显示,无论在症状方面还是功能方面,氢化可的松的疗效都很显著。 步行时的屈曲范围已显示出改善,在某些情况下已达到正常范围,并且在一组12名患者中,这种效果在八周内都保持在显著水平。研究表明,功能改善比疼痛缓解更为缓慢,这可能对未来抗炎药物的评估具有重要意义。 步行时的屈曲范围已显示出改善,在某些情况下已达到正常范围,并且在一组12名患者中,这种效果在八周内都保持在显著水平。研究表明,功能改善比疼痛缓解更为缓慢,这可能对未来抗炎药物的评估具有重要意义。在一项单盲研究中,已将氢化可的松的疗效与关节内注射生理盐水的疗效进行了对比,结果显示,无论在症状方面还是功能方面,氢化可的松的疗效都很显著。