Kothuis B J
Neth J Surg. 1981 Oct;33(4):186-9.
Wound healing following elective laparotomy was studied in 220 patients. The patients were divided into two groups; the first group received preoperative skin disinfection with alcohol 70% and iodine-tincture 2% and, before skin suturing, disinfection with iodine. The second group received preoperative skin disinfection with povidone-iodine 10% (Betadine) and, before skin closure, a 10% povidone-iodine solution was applied to the subcutis and skin edges. Complicated wound healing was seen in 21% of the first and 24% of the second group; wound sepsis rate was 13% and 16% respectively, in the majority of cases following colorectal surgery.
对220例择期剖腹手术患者的伤口愈合情况进行了研究。患者被分为两组；第一组术前用70%酒精和2%碘酒进行皮肤消毒，在皮肤缝合前再用碘酒消毒。第二组术前用10%聚维酮碘（碘伏）进行皮肤消毒，在皮肤缝合前，将10%聚维酮碘溶液涂抹于皮下组织和皮肤边缘。第一组21%、第二组24%出现了复杂的伤口愈合情况；在大多数结直肠手术后的病例中，伤口感染率分别为13%和16%。
