人眼内液对血管内皮细胞迁移的影响。

The effect of human intraocular fluid on vascular endothelial cell migration.

作者信息

Glaser B M, D'Amore P A, Michels R G

出版信息

Ophthalmology. 1981 Sep;88(9):986-91. doi: 10.1016/s0161-6420(81)80016-4.

Abstract

Several recent studies have demonstrated that vascular endothelial cell migration is an essential element of new blood vessel formation. We have recently developed an in vitro assay to study the effect of various substances on vascular endothelial cell migration. We now report the use of this assay to study the effect of human intraocular fluid on endothelial cell migration. We have found a good correlation between the presence of progressive retinal neovascularization in an eye and the ability of vitreous cavity fluid from that eye (obtained at the time of vitrectomy) to stimulate vascular endothelial cell migration in vitro.

摘要

最近的几项研究表明，血管内皮细胞迁移是新血管形成的一个基本要素。我们最近开发了一种体外试验，以研究各种物质对血管内皮细胞迁移的影响。我们现在报告使用该试验来研究人眼内液对内皮细胞迁移的影响。我们发现，一只眼睛中进行性视网膜新生血管形成的存在与该眼玻璃体腔液（在玻璃体切割术时获得）在体外刺激血管内皮细胞迁移的能力之间存在良好的相关性。