Kajosaari M, Backman A, Holopainen E
Allergy. 1981 Aug;36(6):405-10. doi: 10.1111/j.1398-9995.1981.tb01846.x.
Nasal secretion samples from 473 children aged 0--15 years were studied in order to evaluate the role of mast cells in the nasal smear in different types of atopy and food allergy. The occurrence of eosinophils in the nasal secretion and in the blood, and susceptibility to upper respiratory infection were recorded. A mast cell count of more than 20 cells per slide was indicative of atopy and there was a clear correlation between eosinophilia and mastocytosis in the nasal smear. No type of allergy seemed to be significantly predominant in the total material, but in young children aged 0--3 years mastocytosis was clearly related to food allergy. The examination of nasal smears for mast cells is a valuable test in diagnosing atopy in children and especially food allergy among young children. However, the test is not reliable enough to be used as a single screening test.
为评估肥大细胞在不同类型特应性疾病和食物过敏的鼻涂片检查中的作用，对473名0至15岁儿童的鼻分泌物样本进行了研究。记录了鼻分泌物和血液中嗜酸性粒细胞的出现情况以及上呼吸道感染的易感性。每张载玻片上肥大细胞计数超过20个细胞表明存在特应性，并且鼻涂片中嗜酸性粒细胞增多与肥大细胞增多症之间存在明显相关性。在全部样本中，似乎没有哪种过敏类型明显占主导，但在0至3岁的幼儿中，肥大细胞增多症与食物过敏明显相关。对鼻涂片进行肥大细胞检查是诊断儿童特应性疾病尤其是幼儿食物过敏的一项有价值的检测。然而，该检测不够可靠，不能用作单一的筛查检测。
