早期发育阶段实验性诱导肠穿孔的影响。
The effect of experimentally induced intestinal perforation at an early developmental stage.
作者信息
Tibboel D, van der Kamp A W, Molenaar J C
出版信息
J Pediatr Surg. 1981 Dec;16(6):1017-20. doi: 10.1016/s0022-3468(81)80868-8.
In chick embryos we studied the effect on intestinal development of an experimentally induced perforation and a vascular lesion performed at an early developmental stage. The results show that an intestinal perforation will heal, but may lead to intestinal atresia with microscopic signs of meconium peritonitis. Conversely, a vascular lesion induced at an early stage of development does not lead to intestinal atresia, while a vascular lesion performed at a late stage of development does result in intestinal atresia, but without any signs of meconium peritonitis.
在鸡胚中，我们研究了在发育早期进行实验性诱导穿孔和血管损伤对肠道发育的影响。结果表明，肠道穿孔会愈合，但可能导致肠道闭锁并伴有胎粪性腹膜炎的微观迹象。相反，在发育早期诱导的血管损伤不会导致肠道闭锁，而在发育后期进行的血管损伤确实会导致肠道闭锁，但没有任何胎粪性腹膜炎的迹象。
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