Cheix F, Biron A, Bailly C, Mayer M, Pommatau E, Saez S
Nouv Presse Med. 1980 Mar 15;9(13):933-5.
151 women were treated for potentially curable breast cancer. Their tumors were routinely analysed for estrogen receptors by the dextran-coated charcoal technic. Data were analyzed in relation to several parameters: age, age of menstruation, menopausal status, tumor size, TNN staging, axillary node status, nature of treatment. We have examined the pronostic implication of an ER negative content (ER-) in the primary tumor. We have found that the absence of detectable estrogen receptor in primary breast tumor appears to be correlated with a short disease free interval. In positive axillary node patients the value of the disease free interval is significantly shorter in ER- than in ER+ group: 11.5 months versus 23.5 (p less than 0.01).
151名患有潜在可治愈性乳腺癌的女性接受了治疗。她们的肿瘤通过葡聚糖包被活性炭技术常规分析雌激素受体。数据根据几个参数进行分析:年龄、月经初潮年龄、绝经状态、肿瘤大小、TNN分期、腋窝淋巴结状态、治疗性质。我们研究了原发性肿瘤中雌激素受体阴性含量(ER-)的预后意义。我们发现原发性乳腺肿瘤中未检测到雌激素受体似乎与无病生存期短相关。在腋窝淋巴结阳性患者中,ER-组的无病生存期值明显短于ER+组:11.5个月对23.5个月(p<0.01)。