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急性特发性心包炎中的心肌病(作者译)

[Myocardial disease in acute idiopathic pericarditis (author's transl)].

作者信息

Palacios Martinez J, Cosio Mir F G, Penas Lado M, Tascón Pérez J, Oria Vidal J

出版信息

Med Clin (Barc). 1980 Feb 10;74(3):79-83.

PMID:7366277
Abstract

Acute idopathic pericarditis can be accompanied by myocarditis, and in all types of acute pericarditis there are electrocardiographic signs of myocardial lesions. In order to determine the severity of the myocardial disease in acute idiopathic pericarditis, a prospective study has been carried out in a group of 25 patients with this diagnosis. The clinical evaluation included phonomecardiographic measurements of the systolic intervals, Weissler index in 24 cases, and echocardiographic study of the left ventricle in eight cases. Besides that, the serum levels of the myocardial enzymes (GOT, GPT, CPK, and LDH and its isoenzymes) were determined in all cases. The results showed a gallop rhythm in 8 percent of the cases, supraventricular arrhythmias in 4 percent, dysfunction of the left ventricle by systolic intervals and/or echocardiography in 32 percent, and increase of the myocardial enzymes in 24 percent, which represents a global incidence of myocardial disease of 44 percent. However, only three patients presented clinical manifestations of myocardial disease, although the congestive cardiac failure was always secondary to cardiac tamponade and not to myocardial failure. The increase of myocardial enzymes can determine important problems of differential diagnosis with an acute myocardial infarction. The clinical course was favourable in all of the cases, including the ones which showed myocardial disease.

摘要

急性特发性心包炎可伴有心肌炎,在所有类型的急性心包炎中均有心肌损害的心电图表现。为了确定急性特发性心包炎中心肌疾病的严重程度,对一组25例诊断为此病的患者进行了一项前瞻性研究。临床评估包括心音图测量收缩期间期(24例测定了韦斯勒指数)以及8例患者的左心室超声心动图检查。除此之外,所有病例均测定了心肌酶(谷草转氨酶、谷丙转氨酶、肌酸磷酸激酶、乳酸脱氢酶及其同工酶)的血清水平。结果显示,8%的病例出现奔马律,4%出现室上性心律失常,32%的病例通过收缩期间期和/或超声心动图显示左心室功能障碍,24%的病例心肌酶升高,这表明心肌疾病的总体发生率为44%。然而,只有3例患者出现心肌疾病的临床表现,尽管充血性心力衰竭总是继发于心包填塞而非心肌衰竭。心肌酶升高可导致与急性心肌梗死鉴别诊断的重要问题。所有病例,包括那些显示有心肌疾病的病例,临床病程均良好。

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