Kholin V V, Libson I L, Ivanova T F, Bartova V F
Vopr Onkol. 1980;26(6):71-3.
In the paper an attempt was made to determine the optimum single therapeutic dose (otD1( in radiation treatment of 600 patients with laryngeal cancer. It is suggested to take the latter as a standard for adequate dosage in planning fractionation radiotherapy and to use it for calculating the optimum total therapeutic dose (otDt). Both the optimum single therapeutic dose and total dosage equivalent to it may provide for better chances of patients' cure. The analysis indicated that in laryngeal cancer of stage T1--2N0M0 the optimum equivalent single therapeutic dose is mostly likely to be 2700 +/- 60,0 rad while in stage T2N0M0--2850 +/- 50,0 rad.
该论文尝试确定600例喉癌患者放射治疗中的最佳单次治疗剂量(otD1)。建议将其作为制定分次放射治疗合适剂量的标准,并用于计算最佳总治疗剂量(otDt)。最佳单次治疗剂量及其等效总剂量都可能为患者提供更好的治愈机会。分析表明,T1-2N0M0期喉癌的最佳等效单次治疗剂量很可能为2700±60.0拉德,而T2N0M0期为2850±50.0拉德。